The PRWIRE Press Releases https:// 2019-05-15T03:12:10Z CHIROPRACTIC A KEY ROLE IN BACK PAIN RELIEF AND DRUG USE REDUCTION SAYS BIGGEST EVER COMPARATIVE STUDY 2019-05-15T03:12:10Z chiropractic-a-key-role-in-back-pain-relief-and-drug-use-reduction-says-biggest-ever-comparative-study The US study by New Zealand Professor Ian Coulter* is entitled A comparative effectiveness controlled trial evaluated the addition of chiropractic care to usual medical care for patients suffering from low back pain . It was a multi-site, pragmatic, comparative effectiveness study which looked at 750 active duty military personnel with low back pain, aged 18 to 50 years who received either usual medical care or usual medical care plus chiropractic care. Professor Coulter (who is the keynote speaker at this week’s annual conference of the New Zealand Chiropractors’ Association in Christchurch) says: `The most common musculoskeletal condition reported is low back pain. Low back pain is also one of the most frequent reasons that people seek medical care. The burden of low back pain is made worse by the fact that many treatments included under the umbrella of usual medical care, such as NSAIDs, steroid injections, spinal surgery, and opioids, do not significantly decrease pain and may result in serious side effects. Spurred on primarily by the resultant opioid crisis, many government and private organizations, including the FDA, the Joint Commission, and the American College of Physicians are now recommending the use of non-drug, non-surgical therapies for chronic pain, including low back pain. Chiropractic care and/or spinal manipulation delivered by doctors of chiropractic is one of these recommendations.’ The study, published in April found significant improvements in lower back pain intensity and physical disability in favour of those receiving chiropractic care in addition to usual medical care. No related serious adverse events were reported in either group.  Last week Australasian doctors called for a shift in the way pain management is treated in an attempt to tackle New Zealand's opioid "epidemic". The Royal Australasian College of Physicians (RACP) Congress in Auckland heard that there was a need for a "multidisciplinary, evidence-based approach" to pain management, to stamp out New Zealand's "serious" opioid problem. Recent evidence suggests that chiropractic care has an important role to play in reducing opioid prescriptions compared with non-chiropractic care.  There has been a tenfold increase in the number of people over 60 getting help for an addiction to opiate drugs. Figures released by the Ministry of Health show 530 people aged 60 or over are now getting what is called opioid substitution treatment.  In a new meta-analysis and systematic review, presented at the American Academy of Pain Medicine (AAPM) 2019 Annual Meeting in March, patients who visited a chiropractor to help manage a musculoskeletal pain condition were 49% less likely to receive an opioid prescription than their counterparts who went to other healthcare providers . Ten years ago almost no one over the age of 60 had opioid substitution treatment, with just 42 people using it in 2008, but it has increased every year since. The Ministry of Health said the 530 people over 60 who got treatment in 2017 represents a 1200 per cent increase. Professor Coulter says: `Our findings have the potential to impact clinical practice by strengthening the scientific literature regarding the use of chiropractic care in patients with lower back pain.’  New Zealand Chiropractors’ Association President Dr Hayden Thomas comments: `We know there are many more New Zealanders who have a dependence on opioids but have not put their hand up for help. Drugs such as morphine, codeine, Tramadol and Fentanyl are too often given as pain relievers when there are other drug free ways to help manage pain, such as chiropractic.  ‘Some people develop an addiction to these drugs, even when used as prescribed by their doctor. Across the world preventing opioid addiction and overdose is a significant public health priority; and as part of a strategy to reduce opioid use, clinical guidelines in many countries now recommend many drug-free options to be considered as front-line treatment ahead of any medication. ’  Chiropractors are uniquely placed to provide care that specifically focuses on the health of the spine and the relationship between the spine and the nervous system.  New Zealand’s chiropractors are taking the lead to inform, and inspire people to prevent pain and disability by educating the public to have a greater understanding of the relationship between their spine and nervous system, improving their posture, addressing and preventing spinal problems, and engaging in physical activity.  *Professor Ian Coulter is a senior health policy researcher at the RAND Corporation, where he holds the Samueli Institute Chair in Policy for Integrative Medicine, based in Santa Monica, CA. He is a professor at UCLA’s Division of Public Health and Community Dentistry; Pardee RAND Graduate School; and the Southern California University of Health Sciences. ­Ends­ Further Information: Dr Hayden Thomas, Chiropractor 027 299 9939‬ or hayden@chiropractic.org.nz ‬‬ New Record Highs for NZ Activity across Private Equity and Venture-backed Companies 2019-05-02T08:56:03Z new-record-highs-for-nz-activity-across-private-equity-and-venture-backed-companies   ·       Total investment and divestment activity across all investment stages increased to NZ$1.7b, from NZ$990m in 2017. ·       Mid-market investment was above the historical average but decreased to NZ$245m from a record level of NZ$334m in 2017. ·       Early-stage venture investment increased to NZ$270m from NZ$217m in 2017. ·       The average investment transaction value at NZ$17.6m increased from the average of NZ$12.9m in 2017 with significant single transactions lifting the average for both venture and buy-out. EY partner Brad Wheeler, said “increasing market optimism coupled with the figures from 2018 bodes well for expected strong growth to continue into 2019. Fund managers highlighted key factors affecting portfolio companies, including labour availability, challenges of meeting growth plans in a period of global economic uncertainty, and access to capital. The outlook for the New Zealand private capital market remains positive and is slightly improved on 2017.” Mid-market transactions in 2018 included investments by New Zealand domiciled funds including Direct Capital, Maui Capital, Milford Private Equity, Pencarrow Private Equity, Pioneer Capital, Oriens Capital and Waterman Capital. Andrew Frankham, the chair of the New Zealand Private Capital Association said, “The Mid-Market sector continues to be a strong performer with more than $1.9 billion invested in the last decade and $976 million returned to investors to date.” There continues to be a significant amount of capital available from domestic and international private equity funds, providing alternatives for mid-market and large private companies seeking new capital. However, the shortage of capital available for venture capital (series A and B capital raisings) has been long acknowledged. Buy-out private equity activity in 2018 included: Pacific Equity Partners investing in Evolution Healthcare, HgCapital’s acquisition of Orion Health’s Health Rhapsody business and Bain Capital’s investment in Tower. Colin McKinnon New Zealand Private Capital Association executive director said, “The mid-market and the angel network are demonstrating consistent and healthy deepening of the private capital market. The emerging prospects for additional formal venture funds are pleasing. International investor interest in New Zealand companies across all stages continues to provide New Zealand’s private markets with opportunities to grow quality companies and management teams. “Private capital assists in accelerating growth ambitions of New Zealand businesses. Growing businesses with capital and expertise improves productivity, which is good for New Zealand,” said Mr McKinnon.    Ends   About the New Zealand Private Capital Association The New Zealand Private Capital Association is a not-for-profit industry body committed to developing the Venture Capital and Private Equity industry in New Zealand. Its core objectives include the promotion of the industry and the asset class on both a domestic and international basis and working to create a world-class Venture Capital and Private Equity environment. Members include Venture Capital and Private Equity investors, financial organisations, professional advisors, academic organisations and government and quasi- government agencies. © Copyright 2019 New Zealand Private Capital Association   About EY EY is a global leader in assurance, tax, transaction and advisory services. The insights and quality services we deliver help build trust and confidence in the capital markets and in economies the world over. We develop outstanding leaders who team to deliver on our promises to all of our stakeholders. In so doing, we play a critical role in building a better working world for our people, for our clients and for our communities.   EY refers to the global organisation, and may refer to one or more, of the member firms of Ernst & Young Global Limited, each of which is a separate legal entity. Ernst & Young Global Limited, a UK company limited by guarantee, does not provide services to clients. For more information about our organisation, please visit ey.com.   © 2019 Ernst & Young, New Zealand. All Rights Reserved. Remuera Business Association asks Auckland Mayor to intervene in Clonbern Road Car Park Dispute 2019-04-22T21:27:39Z remuera-business-association-asks-auckland-mayor-to-intervene-in-clonbern-road-car-park-dispute The Remuera Business Association (RBA) has asked Auckland Mayor Phil Goff to look at the reasons why, without adequate warning or consultation, AT shut the upper level of the Clonbern Road Car Park in Remuera on 24th March 2019.   RBA Chairman Adrian Barkla says :` We hope that with the Mayor’s intervention that common sense will prevail and access to the Upper Level of the Clonbern Road Car Park can be restored.   `The closure was a great shock to the community and to local businesses. We believe the closure of this part of the Car Park is unwarranted as recent safety tests have concluded that it can be opened with a vehicle weight limit of 2,500kg, not 2,000kg as stated by AT.’   The RBA has provided Phil Goff’s office with the reports from engineering consultants GHD, who carried out tests on the load capacity of the upper level Car Park structure on 14th December 2018 and confirmed that it can be considered safe.   Adrian Barkla adds: `We understand that AT is concerned by people ignoring the signage stating the vehicle weight limit. The Remuera Business Association offered to fund a security guard to enforce the weight limit between the hours of 7am and 7pm but our attempts to negotiate the reopening of the Car Park have fallen on deaf ears.   `As we explained to Phil Goff, the continued closure of the car park and the loss of 70 spaces is damaging the businesses of our members and forcing hundreds of people every day from our community to go elsewhere for goods and services.’   CHIROPRACTIC COULD HELP REDUCE OPIOID DEPENDENCY EPIDEMIC 2019-04-22T21:19:05Z chiropractic-could-help-reduce-opioid-dependency-epidemic Chiropractic is associated with a significant reduction in opioid prescriptions compared with non-chiropractic care, new research suggests.   According to New Zealand Chiropractors’ Association spokesperson, Dr Hayden Thomas, chiropractor :`This is vitally important for New Zealanders as we encounter a worldwide epidemic of opioid addiction.’   There has been a tenfold increase in the number of people over 60 getting help for an addiction to opiate drugs. Figures released by the Ministry of Health this week show 530 people aged 60 or over are now getting what is called opioid substitution treatment.   In a new meta-analysis and systematic review, presented at the American Academy of Pain Medicine (AAPM) 2019 Annual Meeting on 8th March, patients who visited a chiropractor to help manage a musculoskeletal pain condition were 49% less likely to receive an opioid prescription than their counterparts who went to other healthcare providers.   Ten years ago, almost no one over 60 had opioid substitution treatment, with just 42 people using it in 2008, but it has increased every year since. The Ministry of Health said the 530 people over 60 who got treatment in 2017 represents a 1200 per cent increase.   Dr Thomas comments :`We know there are many more New Zealanders who have a dependence on opioids but have not put their hand up for help. Drugs such as morphine, codeine, Tramadol and Fentanyl are too often given as pain relievers when there are other drug free ways to help manage pain, such as chiropractic.   ‘Some people develop an addiction to these drugs, even when used under doctor's guidelines. Across the world preventing opioid addiction and overdose is a significant public health priority; and as part of a strategy to reduce opioid use, clinical guidelines in many countries now recommend many drug-free options to be considered as front-line treatment ahead of any medication.[1]’   The study by the Yale Center for Medical Informatics, Yale School of Medicine, reviewed all the available literature on chiropractic use and opioid prescribing, the researchers selected six studies with a total of 62,000 patients to include in the current analysis.   The data showed that the use of chiropractic care ranged from 11.3% to 51.3%.   The proportion of patients receiving an opioid prescription was lower for those under chiropractic care (range, 12.3% - 57.6%) compared with those not using chiropractic (range, 31.2% - 65.9%).   Chiropractic users were also less likely to receive an opioid prescription, with a risk ratio of 0.51 (95% confidence interval, 0.44 - 0.59; P < .001).   Dr Thomas notes: `Chiropractors provide many of the care recommendations included in the clinical guidelines for the initial management of low back pain, neck pain, and pain due to osteoarthritis of the hip, knee, and hand.   `The researchers said that they knew of "a small but growing amount of scientific literature" suggesting that chiropractic care may be correlated with a reduction in opioid use. But this is the first time a study has systematically reviewed all of the available literature to determine if indeed there was an overall association between the use of chiropractic care and receipt of opioids.’   Chiropractors are uniquely placed to provide care that specifically focuses on the health of the spine and the relationship between the spine and the nervous system.   New Zealand’s chiropractors are taking the lead to inform, and inspire people to prevent pain and disability by educating the public to have a greater understanding of the relationship between their spine and nervous system, improving their posture, addressing and preventing spinal problems, and engaging in physical activity.   The research was supported by the Department of Veterans Affairs, Health Services Research and Development, and the NCMIC Foundation. American Academy of Pain Medicine (AAPM) 2019 Annual Meeting: Abstract 107. Presented March 08, 2019.   [1] Low back pain: a call for action Lancet Volume 391, No. 10137, p2384–2388, 9 June 2018 https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(18)30488-4/fulltext NZVCA APPOINTS NEW CHAIR 2018-12-10T03:08:08Z nzvca-appoints-new-chair Andrew Frankham, Director & CFO of Direct Capital is the new chairman of the New Zealand Private Equity and Venture Capital Association. He succeeds Matt Riley, Executive Director of Waterman Capital. David Bell,  CFO of Oriens Capital, has been reappointed as NZVCA Treasurer. Andrew has been with Direct Capital since January 2010, overseeing all aspects of investment structuring, financial reporting, tax and compliance and investor relations.  Prior to that he was Group Finance Manager for an Auckland private equity expansion investor.   ‘Andrew is a highly respected advocate for private equity markets in New Zealand and shares our understanding that private equity and venture capital firms accelerate the ambition of New Zealand business owners through operational improvement and investment performance,’ says NZVCA Executive Director, Colin McKinnon. Mr McKinnon adds: ‘We are fortunate in New Zealand to share many examples of private capital partnering with companies to improve growth and performance, to share expertise and capital. This ultimately delivers improved productivity, creates jobs and contributes to the national economy.’   ENDS Contact:  ADOLESCENT BACK PAIN MAY HERALD LIFETIME OF ILL HEALTH 2018-10-08T22:36:50Z adolescent-back-pain-may-herald-lifetime-of-ill-health According to new research[1] adolescent back pain may predict poor overall health, and risk of chronic disease throughout life. The New Zealand Chiropractors’ Association (NZCA) is concerned that chiropractic care is an underused option in the management of back pain and spinal health among New Zealand teenagers, and believe it could minimise the unnecessary use of pharmaceuticals[2] and help establish a better foundation for adult wellbeing.   Chiropractor and NZCA spokesperson Dr Cassandra Fairest explains: `This new study in the Journal of Public Health indicates that adolescents who experience back pain more frequently are also more likely to smoke cigarettes, drink alcohol, and report mental health conditions like anxiety and depression. But too few of them are seeking chiropractic care, which was recently cited in a major call to action by the Lancet as a drug free approach to the management of back pain’.   `The authors of this study point out that during adolescence, the prevalence of musculoskeletal pain in general, particularly back pain, rises steeply. Although often dismissed as trivial and fleeting, adolescent back pain is responsible for substantial health care usage, school absence, and interferes with day-to-day activities in some children.’   Researchers used data collected from approximately 6500 teenagers. The proportion of participants reporting smoking, drinking, and missing school rose incrementally with increasing frequency of pain. For example, 14-15 year olds that experienced pain more than once a week were 2-3 times more likely to have drunk alcohol or smoked tobacco in the past month than those who rarely or never had pain.   Similarly, students that experienced back pain more than once a week were around twice as likely to have missed school during the previous school term. The trend with anxiety and depression was less clear, although there was a marked difference between the children who reported no pain, and those who reported frequent pain.   Dr Fairest says: `The researchers found that back pain and unhealthy behaviours not only occur together, but also persist into adulthood. In addition, the developing brain is susceptible to the negative influences of toxic substances, and use in early adolescence may increase the risk of substance abuse and mental health problems in later life.’   The Lancet, one of the world’s most prestigious medical publications, has said in a series of articles that healthcare system changes are crucial to changing behaviour and improving the delivery of effective care for back pain. It recommends integrating and supporting health professionals from diverse disciplines to provide patients with consistent messages about mechanisms, causes, prognosis and natural history of low back pain, as well as the benefits of improved spinal health, physical activity and exercise. Chiropractic is ideally placed to play a pivotal role in this development.   Dr Fairest says: `We do have to ask ourselves why some New Zealanders are still being prescribed pain medication which may cause side effects when chiropractic care may be just as, or even more effective, and offer better long term outcomes? Chiropractors are uniquely placed to provide care that specifically focuses on the health of the spine and the relationship between the spine and the nervous system, both of which are clearly relevant to this population’s presentations. It seems that there’s a disconnect between patient choices and evidence-based guidelines for low back pain based upon what is actually happening within our healthcare system. It appears GP’s are encouraging people to rely on medication and are only considering chiropractic care after pharmaceutical treatments have failed instead of making a referral to a chiropractor a first-line treatment option, as per the research.’   New Zealand’s chiropractors are taking the lead to inform, and inspire people to prevent pain and disability by educating the public to have a greater understanding of the relationship between their spine and nervous system, improving their posture, addressing and preventing spinal problems, and engaging in physical activity.     ­Ends­ Further Information: Dr Cassandra Fairest, Chiropractor 021 242 3073 or cassandra.fairest@chiropractic.org.nz Peter Boyes 027 554 0500 or peter@boyespr.co.nz 1.     [1] S J Kamper, Z A Michaleff, P Campbell, K M Dunn, T P Yamato, R K Hodder, J Wiggers, C M Williams. Back pain, mental health and substance use are associated in adolescents. Journal of Public Health, 2018; DOI: 10.1093/pubmed/fdy129   [2] Low back pain: a call for action Lancet Volume 391, No. 10137, p2384–2388, 9 June 2018 https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(18)30488-4/fulltext     SLEW OF NEW EVIDENCE THAT CHIROPRACTIC IS THE DRUG FREE WAY TO TACKLE BACK PAIN 2018-06-24T09:07:33Z slew-of-new-evidence-that-chiropractic-is-the-drug-free-way-to-tackle-back-pain The New Zealand Chiropractors’ Association welcomes the recent wave of top ranking publications which have come out in favour of chiropractic as an option in the management of back pain.   In its latest issue, The Lancet calls for improved training and support of primary care doctors and other professionals engaged in activity and lifestyle facilitation, such as chiropractors, which could minimise the use of unnecessary medical care[1] and the worldwide overuse of opiate drugs.   Chiropractor and NZCA spokesperson Dr Cassandra Fairest explains: `In a series of articles, The Lancet, one of the world’s most prestigious medical publications, has said that crucial to changing behaviour and improving delivery of effective care for back pain are system changes that integrate and support health professionals from diverse disciplines and care settings to provide patients with consistent messages about mechanisms, causes, prognosis and natural history of low back pain, as well as the benefits of physical activity and exercise. Chiropractic is ideally placed to play a pivotal role in this development.’   A recent study in JAMA Network Open[2] looking at U.S. military personnel found that those who used chiropractic care — along with traditional medical care — had better pain relief outcomes than those who only sought out traditional medical care.   Dr Fairest points out: `It’s a key finding for this group since low back pain is one of the leading causes of disability among U.S. military personnel. Chiropractic care is a natural and safe approach to spinal health, which can provide effective pain relief and may reduce the need for more invasive medical care such as anti-inflammatory medications, opioids, spinal fusions, and epidural steroid injections. Increasingly, with the ongoing opioid crisis in the United States, the medical community there is looking at alternative non-addictive treatments. New Zealand medical doctors cannot be far behind.’   Between 2012 and 2016, a research team evaluated chiropractic care on 750 active-duty U.S. military service members. The mean age of participants was 30.9 years old.   The patients were put into two groups. One group received traditional medical care for back pain along with chiropractic care; the other group only received traditional care. While traditional care can include medication, the chiropractic care included spinal adjustments along with adjunct manual therapies such as ice, heat, cryotherapy, and rehabilitative exercises.   After six weeks, those who got both types of care reported moderately higher improvements in pain intensity and disability compared with those who only received traditional medical care.   Dr Fairest says: `We do have to ask ourselves why some New Zealanders are still being prescribed pain medication when chiropractic care may be just as or even more effective, and offer better long term outcomes? It seems that there’s a disconnect between patient perceptions and evidence-based guidelines for low back pain and what’s actually happening within our healthcare system. Too many family doctors are encouraging people to use medication and are only considering chiropractic care after traditional treatments have failed instead of making it a first-line treatment option, as per the research.’  A recently published study reporting the use of chiropractic in the USA[3] found a substantial proportion of US adults used chiropractic services along with their regular medical care over the past 12 months, and subsequently reported associated positive outcomes for overall well-being and/or specific health problems.’  New Zealand’s chiropractors are taking the lead to inform, educate and inspire people to prevent pain and disability by improving their posture, addressing spinal problems and engaging in physical activity.     ­Ends­ Further Information: Dr Cassandra Fairest, Chiropractor 021 242 3073 or cassandra.fairest@chiropractic.org.nz Peter Boyes 027 554 0500 or peter@boyespr.co.nz [1] Low back pain: a call for action Lancet Volume 391, No. 10137, p2384–2388, 9 June 2018 https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(18)30488-4/fulltext     [2] https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2680417 [3]http://journals.lww.com/spinejournal/Abstract/publishahead/The_prevalence,_patterns,_and_predictors_of.95563.aspx RAINBOW DINNER & AUCTION WITH HELEN CLARK 2018-06-01T23:02:40Z rainbow-dinner-amp-auction-with-helen-clark   Rainbow New Zealand Charitable Trust, Aotearoa’s longest running LGBTI+ charity, is delighted to announce details of its dinner and auction fundraiser on Sunday 9th September at the Cordis Hotel in Auckland.  Building on almost 20 years of fundraising tradition, the evening of fine dining, entertainment and auction will feature internationally renowned guest speaker, Helen Clark, the 37th Prime Minister of New Zealand and former Head of the United Nations Development Programme. The fundraiser will host up to 500 opinion leaders and supporters from the community, business sector and political arena. Tickets are available from www.rainbownzcharitabletrust.org.nz This is the first fundraising event the Trust has held since the GABA Charitable Trust became the Rainbow New Zealand Charitable Trust taking on a national purpose beyond Auckland.  “We are extremely delighted to have a guest of Helen Clark's calibre and profile, and are proud to call her a friend”, says Trust Chair, Gresham Bradley. Gresham comments that while NZ is a world leader in LGBTI+ rights, there was still much work to be done and raising much-needed funds for distribution to the community is Rainbow NZ Trust's purpose.  Since its founding, the Trust has donated over $300,000 to fund a broad range of LGBTIQ+ community organisations, projects and initiatives.  GUEST SPEAKER HELEN CLARK Helen Clark is a long time supporter of the LGBTI+ community.  As the Head of the United Nations Development Programme she addressed the 2016 Rainbow Auckland fund-raiser live by Skype to loud appreciation from the hundreds in attendance at the SkyCity venue.   In 2000, then Prime Minister Helen Clark stood up for the LGBTI+ community during changes to include same-sex relationships in the Matrimonial Property Act. Then in 2002 she issued an apology to the LGBTI+ community on behalf of the Government for many years of discrimination.  More recently as Head of the United Nations Development Programme Helen spoke on International Day Against Homophobia & Transphobia, stating that UNDP supported initiatives to promote understanding of the negative impact of homophobia and transphobia, and to reducing human rights violations.  VIP Function with Helen A strictly limited number of guests will have the opportunity to meet Helen Clark in person at this exclusive event. Beverages and canapes will be served. This private function will take place in the Grey’s Room (set in standing cocktail style) from 5:30pm to 6.30pm prior to the event start at 7:00pm. RAINBOW NEW ZEALAND CHARITABLE TRUST Background: ‘The Rainbow New Zealand Charitable Trust’ has a long history of giving back to the LGBTQI community. Since its founding, the Trust has donated over $300,000 to fund a broad range of LGBTQI organisations, individuals, projects and initiatives. The Trust formally changed its name in January, 2018, becoming the ‘Rainbow New Zealand Charitable Trust’.  The new name adopts the now universally understood term “Rainbow” as reflecting the LGBTQI communities, better communicates the national purpose of the Trust, and more closely aligns the Trust’s name with ‘Rainbow Auckland’ (formerly GABA), ‘Rainbow Tick’ and the many other “Rainbow” organisations in New Zealand. www.rainbownzcharitabletrust.org.nz For more information about the ‘Rainbow Dinner & Auction with Helen Clark’ and the Trust’s ongoing activities please contact: Gresham Bradley,  Chair, Rainbow New Zealand Charitable Trust Mob - 021 473 741 Email - chair@rainbownzcharitabletrust.org.nz www.rainbownzcharitabletrust.org.nz   MOTHERS’ DAY 2018 MESSAGE - BREAST FEEDING PROTECTS MUMS TOO 2018-05-09T08:38:18Z mothers-day-2018-message-breast-feeding-protects-mums-too The Early Life Nutrition Coalition, a subcommittee of the Perinatal Society of Australia and New Zealand (PSANZ) is using Mother’s Day to highlight that while the health benefits of mother’s milk for the newborn child are increasingly understood, many women are unaware of the protective effect of breastfeeding may have on two common cancers effecting New Zealand women.   Early Life Nutrition Coalition New Zealand spokesperson, Dr Clare Wall says breastfeeding has never been more important – both for the mother’s long-term health and for the development of her child’s defences against disease in later life.   Current research reveals the cancer-protecting effect of sustained breastfeeding.   Women who  breastfeed for 12 months reduce their risk of  some breast cancers by 26 per cent. This compares to just a 7 per cent reduction if breastfeeding stops at six months. Women who breastfeed  for 12 months reduce their risk of ovarian cancer by 37 per cent.  This compares to just a 17 per cent reduction if breastfeeding stops at six months.   Dr Wall says: “The message on Mother’s Day is simple – breastfeeding is good for mums and babies and the longer they breastfeed after the introduction of complementary foods there may be  less risk of developing  some types of breast and ovarian cancers.   “Sustained breastfeeding after the introduction of solid foods appears to be the key. It’s perfectly fine to supplement with formula if this allows the mother to keep breastfeeding  for longer.   “More research is needed to establish if breastfeeding a second or third child provides cumulative benefit against cancer risk.”    Dr Wall says: “Cancer is a national health priority, and so there should be strategies to increase the rate and duration of breastfeeding. Breast milk is truly amazing and breastfeeding has never been more important as a preventative health measure for Mum and baby.”   New Zealand women initiate breastfeeding at high rates, but stop early.   Dr Wall says: “New Zealand has great breastfeeding initiation rates, however despite great intentions many infants are not breastfed exclusively to six months, with even fewer babies being fed breast milk12 months. There are significant  benefits to  mothers  own health by breast feeding beyond 6 months."   Ever increasing rates of obesity and allergy may be linked to the decline in the duration of breastfeeding Research confirms that breastfed babies are less likely to develop obesity in later life than those raised on infant formula and the risk is reduced most in those babies that are breast fed for longer. Receiving any breast milk seems to be the key. Breastfed babies are at reduced risk of allergy, notably food allergies and eczema, than those fed with formula. The child’s risk of acute middle ear infection can be reduced through breastfeeding for 12 months.   Dr Wall concludes: “Breast remains best in 2018. The Early Life Nutrition Coalition’s challenge is how best to support mothers and families to get more of these newborns breastfed for longer.”     About the Early Life Nutrition Coalition   “Much of what we say to expectant parents is focused on what not to do while pregnant,” says ELN Coalition Member Dr Clare Wall.   “We’re trying to focus on the positive steps that can be taken. There is a huge opportunity to ensure future generations are getting the best possible start to a healthy and long life,” she says.   “It is the ELN Coalition’s aim to promote actions that can be taken during this critical window of opportunity. While the ELN Coalition would like to facilitate behaviour change in some areas, our aim is to reinforce the positive steps parents can take to enhance the future health of generations to come,” she added.   The New Zealand Health Survey 2016/17 found that: around 1 in 8 children (aged 2–14 years) were obese (12%) a further 21% were children were overweight but not obese 18% of Māori children were obese 29% of Pacific children were obese children living in the most deprived areas were 2.5 times as likely to be obese as children living in the least deprived areas[1] the child obesity rate increased from 8% in 2006/07 to 12% in 2016/17.   Founding members of the Early Life Nutrition Coalition (@EarlyLifeHealth #EarlyLifeHealth #ELNCoalition), which is a sub-committee of the Perinatal Society of Australia and New Zealand, include: Australian Diabetes Educators Association; Australian Diabetes Society; Caring and Living as Neighbours; The Children’s Nutrition Research Centre, University of Queensland; Danone Early Life Nutrition; Developmental Origins of Health and Disease Society; Dietitians Society of Australia; Healthy Start Workforce Project; The Liggins Institute; Menzies Institute for Medical Research; Murdoch Children’s Research Institute; Pharmaceutical Society of Australia; United Way Australia; and the University of Auckland. 
   #Ends 
 For more information : www.psanz.com.au/subcommittees/early-life-nutrition-coalition    About the Early Life Nutrition Coalition The Early Life Nutrition Coalition (@EarlyLifeHealth #EarlyLifeHealth #ELNCoalition) is a formal sub-committee of the Perinatal Society of Australia & New Zealand and its membership comprises: Australian Diabetes Educators Association; Australian Diabetes Society; Caring and Living as Neighbours; The Children’s Nutrition Research Centre, University of Queensland; Danone Early Life Nutrition; Developmental Origins of Health and Disease Society; Dietitians Association of Australia; Healthy Start Workforce Project; The Liggins Institute; Menzies Institute for Medical Research; Murdoch Children’s Research Institute; Pharmaceutical Society of Australia; United Way Australia; and the University of Auckland [1] Adjusted for differences in age, sex and ethnicity.   A record year for NZ mid-market and venture-backed companies 2018-05-09T08:32:57Z a-record-year-for-nz-mid-market-and-venture-backed-companies The New Zealand Private Equity and Venture Capital Monitor, released today, highlights a strong growth in investment in New Zealand businesses in 2017. ·       Mid-market investment increased to NZ$334m, twice the 10-year average of $161m. ·       Early-stage venture investment increased to $217m from NZ$92m in 2016. ·       Total investment and divestment activity across all investment stages reduced to NZ$990m from NZ$1,557m in 2016. ·       The average deal value at NZ$12.9m was lower than the average of NZ$18.2m in 2016 but still well above the averages over the last 10 years.   EY partner Brad Wheeler says it has been a record year for mid-market investment activity, at $333.7m. “This was driven by a higher average investment value across a wider range of transactions. It was also a record year for venture investment, with higher levels of foreign capital working with domestic early-stage fund managers to fast-track high-growth innovation.” Mid-market deals in 2017 included investments by New Zealand domiciled funds such as Direct Capital, Waterman Capital, Pioneer Capital, Pencarrow Private Equity, Maui Capital and Oriens Capital.  ‘Investment in private New Zealand companies continues to be led by local managers striving to accelerate growth and drive productivity gains,” says Matt Riley, chair of NZVCA. “Private equity and venture-backed businesses often embrace and overcome challenges that would not have been possible without the capital and skills the industry provides.”    Short-term optimism has reduced since last year and remains subdued further out due to continuing expectations of global market volatility, increasing interest rates and of the potential impact of increasing regulation.’   Buy-out private equity activity in 2017 included: Navis Capital Partners 75% stake in Mainland Poultry; Mercury Capital acquired half of Nirvana Health; and Strait Shipping was acquired by Australian based CHAMP Private Equity.   Colin McKinnon, NZVCA executive director, says: “The international interest in venture investment, alongside New Zealand investors and managers, confirms the growing presence of good quality companies and management teams. The mid-market is maturing rapidly and the angel network is developing a healthy innovation eco-system. It is pleasing see the breadth of growth across stages this year which enhances the reputation of New Zealand private markets. “Private equity and venture capital accelerate growth for New Zealand businesses. Growing businesses with capital and expertise improves productivity, which is good for business, and good for New Zealand.”    Ends     About the New Zealand Private Equity & Venture Capital Association The NZVCA is a not-for-profit industry body committed to developing the Venture Capital and Private Equity industry in New Zealand. Its core objectives include the promotion of the industry and the asset class on both a domestic and international basis and working to create a world-class Venture Capital and Private Equity environment. Members include Venture Capital and Private Equity investors, financial organisations, professional advisors, academic organisations and government and quasi- government agencies. © Copyright 2018 New Zealand Private Equity and Venture Capital Association   About EY EY is a global leader in assurance, tax, transaction and advisory services. The insights and quality services we deliver help build trust and confidence in the capital markets and in economies the world over. We develop outstanding leaders who team to deliver on our promises to all of our stakeholders. In so doing, we play a critical role in building a better working world for our people, for our clients and for our communities.   EY refers to the global organisation, and may refer to one or more, of the member firms of Ernst & Young Global Limited, each of which is a separate legal entity. Ernst & Young Global Limited, a UK company limited by guarantee, does not provide services to clients. For more information about our organisation, please visit ey.com.   © 2017 Ernst & Young, New Zealand. All Rights Reserved. NZ CHIROPRACTORS’ ASSOCIATION SAYS INTEGRATED HEALTHCARE IS SOLUTION TO REDUCING PAINKILLER CONSUMPTION 2017-12-12T03:14:06Z nz-chiropractors-association-says-integrated-healthcare-is-solution-to-reducing-painkiller-consumption Chiropractic care could be a cost-effective solution to the overuse of painkillers and better management of chronic pain if there was better integration of primary healthcare services, says the New Zealand Chiropractors’ Association (NZCA).   Chiropractor and NZCA spokesperson Dr Cassandra Fairest explains: ‘Primary health care professionals need to improve communication with each other. A recently published study of the use of chiropractic in the USA[1] found a substantial proportion of US adults used chiropractic services along with their regular medical care over the past 12 months, and subsequently reported associated positive outcomes for overall well-being and/or specific health problems.  New Zealand’s chiropractors are taking the lead to inform, educate and inspire people to prevent pain and disability by engaging in physical activity.  However, research shows that in too many instances patient care is not optimised because of inadequate communications between the health care practitioners[2].’   A study published last year concluded communication barriers may be viewed as a major contributing factor to the ongoing chronic pain management/chronic painkiller and opioid overuse problem2.   Dr Fairest adds: `Chiropractic care can play a major role in the management of chronic pain for many patients. However, often patients may be receiving care from more than one primary health care professional. For example, the family chiropractor may not know what the GP is advising, or vice versa. Because of this lack of understanding between professions and their communication, the quality of care may be deficient which could contribute to poorer health outcomes for New Zealanders.’   She points out: `We were really pleased to see our medical colleagues are now recommending people become more active to reduce inflammation and associated diseases. This is something chiropractors have been strongly advocating for many years.’   Further to this, a major international study published in the Lancet[3] demonstrated that simply increasing physical activity is a widely applicable, low cost global strategy that could reduce deaths and cardiovascular disease in middle age.   The NZCA has developed a Just Start Walking programme to put a spring in your step. The NZCA also recommends getting a spinal check-up with your family chiropractor prior to starting any new exercise regime. An NZCA chiropractor will evaluate your spine and nervous system for dysfunction and analyse your posture for imbalances, which may be negatively impacting upon your movement and overall health.   Some Tips on How to Get Started ●      Visit your local NZCA chiropractor for a spinal health check up ●      Commit to daily 30 minute walking programme ●      Start slowly – set achievable targets to prevent injury and to motivate you ●      Find a friend or work colleague to walk with ●      Wear appropriate footwear which is designed for walking ●      Warm up with a few gentle stretching exercises at the start and end of your walk ●      Drink plenty of water and have regular breaks and healthy snacks ●      Mix it up – walking different routes, at different speeds with different inclines ●      Enjoy your walking and the benefits it can bring!   ­Ends­ Further Information: Dr Cassandra Fairest, Chiropractor 021 242 3073 or cassandra.fairest@chiropractic.org.nz [1]http://journals.lww.com/spinejournal/Abstract/publishahead/The_prevalence,_patterns,_and_predictors_of.95563.aspx [2] https://bmccomplementalternmed.biomedcentral.com/articles/10.1186/s12906-016-1005-4 [3] http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(17)31634-3/fulltext?elsca1=tlpr NZVCA Media Release Q1 2017 Data 2017-10-31T20:48:11Z nzvca-media-release-q1-2017-data Cambridge Associates Comment – NZVCA Media Release Q1 2017 Data October 2017 Australasian private equity and venture capital funds delivered a 18% net return, in New Zealand dollars, for the 3-years ending 31 March 2017, according to data provided by Cambridge Associates.  Investors have enjoyed attractive returns driven by strong distributions in excess of $3.0 billion back to investors during the past year.  Australasian private equity and venture capital funds have strongly outperformed local listed market comparisons for three-year, five-year and 10-year periods.  The 15-year annualised return on Australasian private equity and venture capital was 11 per cent compared with a public market equivalent 5 per cent for the S&P ASX 300, a value-add of 600 basis points.  A similar theme of strong returns and record distributions has occurred across global private equity and venture capital markets over the same 15 year period. Eugene Snyman, Managing Director at Cambridge Associates, presented the firm’s research findings and performance analysis of 94 Australasian private equity and venture capital funds during the NZVCA Annual Private Equity and Venture Capital Conference held in Queenstown on 19 October.  Eugene Snyman said: “The returns generated by Australasian private equity and venture capital funds makes for a compelling opportunity for private investments to add meaningful value to portfolios of long-term investors who are seeking to build portfolios capable of generating the alpha required to achieve their overall investment objectives.  Rigorous investment and operational due diligence coupled with discipline in manger selection continue to be paramount to successfully investing in private equity and venture capital.”     In the analysis by Cambridge Associates, private equity and venture capital investments in New Zealand companies represented well diversified sector exposure, but relative to local listed markets, had greater exposure to healthcare, consumer and information technology sectors.  Private equity and venture capital investments into mid-market New Zealand companies have been particularly strong, generating net returns of 25%.  About Cambridge Associates Cambridge Associates is a global investment firm founded in 1973.  The firm helps more than 1,000 endowments, foundations, pension plans, and private clients maximize their impact on the world by building custom investment portfolios aimed at generating outperformance across all asset classes.  Working alongside its early clients, among them leading university endowments, the firm pioneered the strategy of high-equity orientation and broad diversification, which since the 1980s has been a primary driver of performance for institutional investors. Cambridge Associates delivers a range of services, including outsourced CIO; investment consulting; and access to investment research and tools across the continuum of global asset classes.   Cambridge Associates has more than 1,200 employees and maintains offices in Boston; Arlington, VA; Beijing; Dallas; London; Menlo Park, CA; New York; San Francisco; Singapore; Sydney; and Toronto. Cambridge Associates consists of five global investment consulting affiliates that are all under common ownership and control. For more information, please visit www.cambridgeassociates.com.   GET YOUR BACK IN ACTION AND STAY WELL SAY NEW ZEALAND CHIROPRACTORS 2017-10-15T01:27:03Z get-your-back-in-action-and-stay-well-say-new-zealand-chiropractors Research is showing that increasing physical activity to strengthen your back is one of the most effective ways of ensuring great long term health says the New Zealand Chiropractors’ Association (NZCA), as the primary health care organisation marks World Spine Day 2017 (16th October). Chiropractor and NZCA spokesperson Dr Cassandra Fairest explains: ‘On this year’s World Spine Day we’re encouraging everyone to get Your Back In Action. Spinal disorders are amongst one of the leading causes of disability in the world today. When people cannot move or get around adequately it impacts upon their quality of life. This year, New Zealand’s chiropractors are taking the lead to inform, educate and inspire people to prevent pain and disability by engaging in physical activity and Get Your Back In Action!’   Too much time watching TV or online may lead to an early death from dementia, Parkinson's disease or diabetes, according to Australian research published this month[1]. The study found that engaging daily in a two hour session of either a favourite TV show or an online gaming activity increased the risk of an inflammatory disease-related death by 54 per cent.   Chronic inflammation is now considered to be central – amongst other factors – to many illnesses including the three diseases researched. Researchers at the Baker Heart and Diabetes Institute in Melbourne said the findings, based on nearly 9,000 adults, stem from prolonged sitting.   Dr Fairest explains: `If you want to binge watch the latest Netflix series or any multiple episodes in one sitting, you should get up regularly and stretch your legs. You could engage in some exercises from your family chiropractor, while you are up on your feet.’ Further to this, a major international study (the PURE study recently published in the Lancet[2] which considered the correlation between physical activity on mortality and cardiovascular disease in 130,000 people from 17 countries) demonstrated that simply increasing physical activity is a widely applicable, low cost global strategy that could reduce deaths and CVD in middle age.   According to the largest study of its kind, Alzheimer's disease may be avoided by following a healthy lifestyle - even if you're predisposed to developing it[3].  Researchers at the University of California in Irvine began the '90+ Study' in 2003. Tests were carried out on 1,700 participants every six months to monitor their cognitive ability. Post-mortems were conducted upon their death and it was noted that some participants appeared to have been at risk of developing Alzheimers but had ‘cognitive resilience’ and therefore did not develop the disease.   Dr Fairest explains: `Exercising, monitoring blood pressure and watching less TV are the three key factors that will help to build body-brain resilience and minimise the risk of developing Alzheimers.  The researchers suggested the reason for such 'cognitive resilience' in those who should have developed dementia but remained free of it was due to leading a healthy lifestyle.’   The NZCA has developed a Just Start Walking programme to put a spring in your step. The Association also recommends getting a spinal check-up with your family chiropractor prior to starting any new exercise regime. An NZCA chiropractor will evaluate your spine and nervous system for dysfunction and analyse your posture for imbalances, which may be negatively impacting upon your overall health.   Some Tips on How to Get Started ●      Visit your local NZCA chiropractor for a spinal system check up ●      Commit to a nine week walking programme ●      Start slowly – set achievable targets to prevent injury and to motivate you ●      Find a friend or work colleague to walk with ●      Wear appropriate footwear which is designed for walking ●      Warm up with gentle stretching exercises at the start and end of your walk ●      Drink plenty of water and have regular breaks and healthy snacks ●      Mix it up – walking different routes, at different speeds with different inclines ●      Enjoy your walking! ­Ends­ Further Information: Dr Cassandra Fairest, Chiropractor 021 242 3073 or cassandra.fairest@chiropractic.org.nz Peter Boyes 027 554 0500 or peter@boyespr.co.nz [1] https://www.baker.edu.au/news/media-releases/binge-watching-tv [2] http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(17)31634-3/fulltext?elsca1=tlpr [3] http://www.dailymail.co.uk/health/article-4895426/Don-t-want-dementia-Turn-TV.html#ixzz4t67mqUmt PUT YOUR BEST FOOT FORWARD FOR BETTER HEALTH SAY NEW ZEALAND CHIROPRACTORS 2017-09-10T21:13:56Z put-your-best-foot-forward-for-better-health-say-new-zealand-chiropractors Taking care of your feet combined with chiropractic care may have a significant effect on how you feel according to the New Zealand Chiropractors’ Association (NZCA). Chiropractor and NZCA spokesperson Dr Cassandra Fairest explains: ‘We’ve warned people about the effects of high heels and challenging footwear on health[1] but the latest research suggests that modifying what you wear on your feet combined with chiropractic care may have a significant effect on foot function as well as decreased pain throughout the rest of the body, especially the spine.’ A new study [2]suggests custom orthotics (shoe inserts) in combination with chiropractic care are significantly effective for relieving pain and improving function in patients with chronic low back pain. The randomised study of 225 adult subjects with symptomatic lower back pain for three months found that patients who received custom-made orthotics and those who received custom orthotics plus chiropractic care experienced significant improvements in pain and function compared to patients receiving no intervention. Comparing the orthotics-only and "plus" groups, the patients receiving chiropractic care achieved greater improvements in function, but similar pain relief was found in the orthotics-only group. Dr Fairest adds: `How you walk and how you look after your feet can have a tremendous impact on posture, spinal function and overall health. We know that for every 20 minutes you spend sitting, it takes your spine about 30 minutes of standing or 5 minutes of walking to recover.[3],[4] Spring is the perfect time of year to gently increase activity after the winter months. Walking regularly will also help improve your immune system, blood and lymph circulation, enhance mood and energy levels, and help maintain good levels of bone density.[5]’ The NZCA has developed a Just Start Walking programme to put a spring in your step but recommends getting a spinal check-up with your family chiropractor prior to starting any new exercise regime. An NZCA chiropractor will evaluate your spine and nervous system for dysfunction and analyse your posture for imbalances, two conditions which may predispose you to walking related injuries.   Some Tips on How to Get Started ●      Visit your local NZCA chiropractor for a spinal system check up ●      Commit to a nine week walking programme ●      Start slowly – set achievable targets to prevent injury and to motivate you ●      Find a friend or work colleague to walk with ●      Wear appropriate footwear which is designed for walking ●      Warm up with gentle stretching exercises at the start and end of your walk ●      Drink plenty of water and have regular breaks and healthy snacks ●      Mix it up – walking different routes, at different speeds with different inclines ●      Enjoy your walking!             ­Ends­   Further Information: Dr Cassandra Fairest, Chiropractor 021 242 3073 or cassandra.fairest@chiropractic.org.nz Peter Boyes 027 554 0500 or peter@boyespr.co.nz     [1] http://www.huffingtonpost.com/entry/high-heels-can-be-causing-back-knee-and-hip-pain-and_us_59042f84e4b084f59b49f946 [2] http://www.archives-pmr.org/article/S0003-9993(17)30262-9/pdf [3] Restaino RM, Holwerda SW, Credeur DP, Fadel PJ, Padilla J. Impact of prolonged sitting on lower and upper limb micro- and macrovascular dilator function. Experimental Physiology 2015;100(7):829-38. [4] http://www.sca-chiropractic.org/index.php?option=com_content&view=article&id=77&Itemid=79 [5] http://www.who.int/mediacentre/factsheets/fs385/en/ Significant New Breast Cancer Treatment Available in New Zealand 2017-09-03T07:34:37Z significant-new-breast-cancer-treatment-available-in-new-zealand An entirely new form of anti-cancer therapy that works to apply the brakes to cancer cell division and growth can now be prescribed for New Zealand women with a common and incurable type of breast cancer.1   Cancer experts welcome the approval of IBRANCE® (palbociclib) by MEDSAFE to treat an invasive form of breast cancer that has spread to other parts of the body.1   IBRANCE can be used in combination with hormonal therapy* to treat the 60 per cent of women2 with advanced or metastatic breast cancer whose cancer cells are hormone-receptor positive (HR-positive) and human epidermal growth factor receptor 2 negative (HER2-negative).1   Dr Reuben Broom, Medical Oncologist from Auckland explained that this class of therapy represents a significant advance for more than 400 New Zealand women3 who are diagnosed every year with this common type of advanced breast cancer.   He said: “Palbociclib represents a major breakthrough in that it can delay the onset of resistance to hormone (endocrine) therapy by interfering with the cell-cycle of these cancer cells. In trials, the addition of palbociclib to endocrine therapy increases the likelihood of tumour shrinkage and more or less doubles the duration of time to progression (tumour growth) and the consequent need to change therapy”1,4.    “Because palbociclib can delay the need to commence patients on chemotherapy, it allows women to continue living without the disruption often associated with chemotherapy”.   “While most women with early breast cancer are cured of their disease with surgery and post-operative (adjuvant) therapy, there is a small but significant proportion of women whose disease returns. In breast cancer it commonly recurs in a multifocal or widespread pattern so is usually considered incurable”.   “For this most common type of breast cancer, we typically treat their disease with anti-hormonal (endocrine) therapy. The effectiveness of this approach is variable depending on factors such as hormone-sensitivity and prior therapy. The advantage of endocrine therapy is it can be continued as long as it is working and is usually better tolerated then chemotherapy, which often ties patients to a cancer infusion centre. However, resistance to single-agent endocrine therapy inevitably develops and then we typically move patients to chemotherapy.”   Palbociclib is an oral therapy taken daily, for 3 weeks on and one week off in a recurring pattern1.   Palbociclib is generally well tolerated with the most common side effects including a lowering of white blood cell counts (requires monitoring), fatigue and general stomach disturbance (usually mild and manageable)1.   Available in more than 60 countries4 around the world, IBRANCE belongs to a class of medicine known as CDK4/6 inhibitors that acts to disrupt the proliferation of cancer cells.1   Dr Broom explained: “The growth of hormone sensitive breast cancer is dependent on factors called cyclin-dependent kinases 4 and 6 (CDK4 and CDK6), which promote the progression through the cell cycle leading to cell division.  This has therefore become a natural and obvious target for a therapy to prevent further growth and development of cancer. Interestingly, it may also help overcome or prevent the development of hormone resistance.  Palbociclib is such an agent (inhibitor of CDK4 and CDK6)”.   Dr Broom added: “This welcome news of palbociclib registration will make it somewhat simpler for patients who wish to pursue this approach to access palbociclib. Until now there have only been a handful of patients in New Zealand who have accessed it, and for these patients access has typically been a challenge.”   Ibrance® (palbociclib) is not currently funded and patients will need to pay for this medicine.   About metastatic breast cancer and its treatment   There are several types and sub-types of disease referred to as breast cancer. As such, identifying the specific type of cancer is fundamental to determining appropriate therapy.5,6,7   Treatment options for metastatic breast cancer depend on several factors, including where the cancer has spread to, the level of oestrogen receptors found inside the breast cancer cell, and the level of the HER2 gene or HER2 protein on the surface of cancer cells.5,6,7   Cancers that are hormone-receptor-positive use the hormones oestrogen to grow and spread.5,6,7   When a breast cancer cell has abnormally high levels of the HER2 gene or HER2 protein, it is called HER2-positive. The cancer is HER2-negative when it does not have high levels of the HER2 gene or protein.5,6,7   The majority of patients with metastatic breast cancer have HER2-negative breast cancer. If HER2-negative breast cancer is also oestrogen receptor positive, the most common treatment is hormonal therapy, followed by chemotherapy.5,6,7   About Pfizer New Zealand: Working together for a healthier world™ At Pfizer, we apply science and our global resources to improve health and well being at every stage of life. We strive to set the standard for quality, safety and value in the discovery, development and manufacturing of medicines. Our diversified global health care portfolio includes biologic and small molecule medicines and vaccines, and many of the world's best-known consumer products. Every day, Pfizer colleagues work across developed and emerging markets to advance wellness, prevention, treatments and cures that challenge the most feared diseases of our time. Consistent with our responsibility as the world's leading biopharmaceutical company, we also collaborate with healthcare providers, governments and local communities to support and expand access to reliable, affordable health care around the world. For more than 150 years, Pfizer has worked in countries around the world to make a difference for all who rely on us. For more information please visit www.pfizer.co.nz         DIRECT TO CONSUMER MANDATORY IBRANCE® (palbociclib 75 mg, 100 mg and 125 mg) Capsules IBRANCE (palbociclib) is an unfunded prescription medicine used to treat HR+, HER2- advanced breast cancer taken in combination with an aromatase inhibitor or fulvestrant. IBRANCE has risks and benefits.  Do not take IBRANCE if you are allergic to palbociclib or any of the other ingredients in IBRANCE capsules. Caution is needed if you are premenopausal or perimenopausal, have or have had abnormal blood test results, problems with your liver or kidneys, are lactose intolerant, are pregnant or planning to become pregnant or are breastfeeding.  Tell your doctor if you are taking any other medicines. Common side effects include infection, abnormal blood test results, tiredness, feeling sick or vomiting, diarrhoea, sore mouth, lips or tongue, hair loss, loss of appetite, nose bleed, skin rash, change in sense of taste, blurred vision, increased tearing or dry eyes, shortness of breath, bleeding or bruising more easily than usual.  If symptoms continue or you have side effects, see your doctor, pharmacist or healthcare professional. Ask your doctor if IBRANCE is right for you.  Use strictly as directed. Contains 75 mg, 100 mg or 125 mg of palbociclib. You will need to pay for this medicine and normal doctor’s fees apply. Further information on IBRANCE is available from Medsafe www.medsafe.govt.nz or Pfizer New Zealand Limited, Auckland, www.pfizer.co.nz  Ph. 0800 736 363. V10817 ENDS   Media Contacts Peter Boyes on behalf of Pfizer Peter Boyes peter@boyespr.co.nz Tammy Dickinson Pfizer New Zealand Tel: 0275 540 500 Tel: 021 723 982   Tammy.Dickinson@pfizer.com     References: 1.   IBRANCE Datasheet June 2017 2.   Rocca A, et al. Palbociclib (pd 0332991): targeting the cell cycle machinery in breast cancer. Expert Opin Pharmacother. 2014;15(3):407-420. 3.   www.breastcancer.org.nz/content/metavivors-stories 4.   Pfizer Data on file 5.   www.breastcancerfoundation.org.nz/breast-cancer/advanced-breast-cancer 6.   www.breastcancer.org.nz/content/treatment 7.    American Society for Clinical Oncology. Treatment of Advanced HER2-Negative Breast Cancer. Available at: www.cancer.net/research-and-advocacy/asco-care-and-treatment-recommendations-patients/treatment-advanced-her2-negative-breast-cancer IBRANCE(R) is a registered trademark. PP-IBR-NZL-0010. NA 9380. Prepared in August 2017